Ya-Wen Kuo
Chung Hwa University of Medical Technology, Taiwan
Title: Association between body mass index and recurrent stroke in ischemic stroke patients
Biography
Biography: Ya-Wen Kuo
Abstract
An associate between body mass index (BMI) and recurrent stroke outcome have been reported, but there was an inverse results. We therefore conducted a meta-analysis to see if there is an increased risk of recurrent stroke for obese or underweight stroke patients. PubMed and Embase from January 1966 to March 2016 were searched to identify relevant studies. Inclusion criteria were case control studies, patients with first ischemic stroke. The major outcome was recurrent stroke event. The pooled relative risks with the corresponding 95% confidence intervals were calculated by using random-effects model. The systematic search identified 3 studies, with a total of 44, 578 participants. Pooling the results showed that recurrent stroke was significantly lower in obesity patients (OR= 0.875; confidence interval, 0.753 – 1.016) and overweight patients (OR =0.901; confidence interval, 0.85 – 0.956) while significantly higher in underweight patients (OR = 1.662; confidence interval, 0.777 – 3.556) compared with normal weight ischemic stroke patients. The meta-analysis shows that ischemic stroke patients who are obesity or overweight have a better progosis when compared with ischemic stroke patients with underweight or normal weight. We suggest that the body weight management was recommended in patients after first time ischemic stroke because the assessment of body weight seems often undervalued.